学习经历
2012.9—2017.6,中国农业大学,生物信息学,理学博士
2008.9—2012.6,河北大学,生物科学,理学学士
工作经历
2017.9至今,河北农业大学生命科学学院分子生物学与生物信息学系
荣誉称号及社会兼职
1. 河北省植物生理与分子生物学会常务理事(2024-)
2. 河北省冀青之星
3. 河北农业大学学报编委
4. Journal of Integrative Agriculture、New Plant Protection等期刊青年编委
教学工作
本科生课程:
1. 专业核心课《生物数据库与软件应用》
2. 专业选修课《生物信息技术前沿》
研究生课程:
《功能基因研究进展》
主要研究方向及领域
目前的研究方向主要包括:
1)表观遗传学与植物抗病;
2)植物病原真菌致病机制;
3)生物信息数据平台。
主持课题项目
1. 国家自然科学基金面上项目,ZmREL2乙酰化参与JA信号通路调控玉米抗茎腐病的机制研究,2024.1-2027.12,主持;
2. 国家自然科学基金青年项目,玉米组蛋白去乙酰化酶HDA101参与抵抗禾谷镰孢侵染的机制研究, 2020.1-2022.12,主持;
3. 河北省教育厅青年拔尖人才项目,ZmBT4调控玉米抵抗禾谷镰孢侵染的分子机制, 2022.4-2024.12,主持;
4. 河北省自然科学基金,玉米组蛋白去乙酰化酶HDA101参与抵抗禾谷镰孢侵染的调控机制,2019.1-2021.12,主持;
5. 保定市科技计划项目,玉米TOPLESS蛋白ZmREL2参与抵抗大斑病菌侵染的机制研究,2024.9-2026.12,主持;
6. 华北作物改良与调控国家重点实验室自主研究课题,玉米根际有益微生物的筛选与应用,2023.1-2025.12,主持;
7 横向课题,单细胞测序数据分析流程优化与应用,2024.1-2027.12,主持;
8. 河北农业大学引进人才项目,拟南芥MYB73参与抗病的分子机制, 2017.9-2022.12,主持;
9. 国家自然科学基金面上项目,灰葡萄孢犬尿氨酸途径关键酶基因BcKMO影响病菌致病力的机制,2020.01-2023.12,参与;
10. 河北省重点研发计划项目,植物多功能复合微生态制剂的研发与应用, 2019.07-2022.06,参与。
代表性学术成果
研究论文(*通讯作者):
1. Chromosome-level genome of Iris domestica reveals genes involved in isoflavonoid biosynthesis,Crop Journal, 2026. (通讯作者)
2. Genome-wide identification and expression analysis of RBR-type ubiquitin ligase family genes reveal the role of ZmIBR10 in maize disease resistance,BMC Plant Biology,2026. (通讯作者)
3. Multi-omics analysis of the Cd response mechanism in Iris domestica and the role of IdNRAMP2 in Cd translocation,Plant Physiology and Biochemistry,2025. (通讯作者)
4. Molecular characterisation of the peroxidase gene family in Botrytis cinerea and the role of BcPRD7 in virulence,Molecular Plant Pathology,2025. (通讯作者)
5. Biocontrol Potential of Bacillus subtilis A3 Against Corn Stalk Rot and Its Impact on Root-Associated Microbial Communities,Agronomy,2025. (通讯作者)
6. Root-associated microbial diversity and metabolomics in maize resistance to stalk rot,2024,Frontiers in Microbiology. (第一作者)
7. Function of ZmBT2a gene in resistance to pathogen infection in maize. Phytopathology Research. 2024. (通讯作者)
2. FGCD: a database of fungal gene clusters related to secondary metabolism. Database (Oxford), 2024. (通讯作者)
3. ZmMYC7 directly regulates ZmERF147 to increase maize resistance to Fusarium graminearum. Crop Journal, 2023. (共同第一作者)
4. Identification and expression analysis of sugar transporter family genes reveal the role of ZmSTP2 and ZmSTP20 in maize disease resistance. Journal of Integrative Agriculture, 2023. (通讯作者)
5. The first genome sequence resource of Tilletia setariae, the causal agent of Foxtail millet stinking smut disease. Phytopathology, 2022.(第一作者)
6. Global analysis of lysine 2-hydroxyisobutyrylation during Fusarium graminearum infection in maize. Frontiers in Plant Science, 2022. (第一作者)
7. Maize stalk rot caused by Fusarium graminearum alters soil microbial composition and is directly inhibited by Bacillus siamensis isolated from rhizosphere soil. Frontiers in Microbiology, 2022. (第一作者)
8. BcSDR1 is involved in regulation of glucose transport and cAMP and MAPK signaling pathways in Botrytis cinerea. Journal of Integrative Agriculture, 2022. (通讯作者)
9. PolyReco: A method to automatically label collinear regions and recognize polyploidy events based on the KS dotplot. Frontiers in Genetics, 2022.(共同第一作者)
10. An intelligent recognition method of chromosome rearrangement patterns based on information entropy. Scientific Reports, 2022.(通讯作者)
11. Comparative proteomic analysis of the defense response to Gibberella stalk rot in maize and reveal that ZmWRKY83 is involved in plant disease resistance. Frontiers in Plant Science, 2021.(通讯作者)
12. A genome resource of Setosphaeria turcica, causal agent of northern leaf blight of maize. Phytopathology, 2020.(共同第一作者)
13. In silico analysis of maize HDACs with an emphasis on their response to biotic and abiotic stresses. PeerJ, 2020. (第一作者)
14. The kynurenine 3-monooxygenase encoding gene, BcKMO, is involved in the growth, development, and pathogenicity of Botrytis cinerea. Frontiers in Microbiology, 2018. (第一作者)
15. PCSD: A plant chromatin state database. Nucleic Acids Research, 2018. (共同第一作者)
16. Differential deposition of H2A.Z in combination with histone modifications within related genes in rice callus and seedling. Plant Journal, 2016. (第一作者)
17. Down-regulation of OsSPX1 caused semi-male sterility, resulting in reduction of grain yield in rice. Plant Biotechnology Journal, 2016. (共同第一作者)
发明专利
张康, 邢继红, 杜月, 郭浩, 曹宏哲, 司贺龙, 董金皋. 一株贝莱斯芽孢杆菌及其在植物病害防治中的应用. ZL202111499658.8, 2021-12-09.
创新创业竞赛获奖
1. 2021,河北省“挑战杯”全国大学生课外学术科技作品竞赛特等奖,第一指导教师;
2. 2022,河北省“挑战杯”全国大学生课外学术科技作品竞赛一等奖,第一指导教师;
3. 2023,河北省“挑战杯”全国大学生课外学术科技作品竞赛二等奖,第二指导教师;
4. 2023,河北省“挑战杯”全国大学生课外学术科技作品竞赛三等奖,第一指导教师。
5. 2024,河北省“挑战杯”全国大学生课外学术科技作品竞赛一等奖,共同指导教师。